Oral side effects are prevalent in individuals experiencing oncology treatment. Compliance with meticulous home care is essential and should be individualized based on risk factors and the current state of health. Oncology therapies result in a host of oral side effects including tooth hypersensitivity, impaired taste, xerostomia, destruction of tooth enamel due to vomiting, and mucositis along with discomfort and pain. The goals in treating mucositis are relieving pain and preventing secondary infections through home oral hygiene and mouth rinses. Intravenous bisphosphonate therapy this is not oncologic treatment. Perhaps the author intends to mean “chemotherapy” can lead to osteonecrosis of the jaw, especially after a tooth extraction or oral surgery. It is important for dental professionals to be familiar with these side effects and discern how to counsel their patients appropriately.