The widespread use of latex products in barrier infection control products has resulted in an increasing number of allergic reactions in patients and healthcare workers. There are several types of immune responses to latex that can occur, including life-threatening anaphylactic shock. Tests can determine whether or not a person is sensitive to latex, and the type of immune response. Latex sensitivity is particularly prevalent in healthcare workers and patients with Spina Bifida. If latex sensitivity is suspected in a patient or healthcare worker, alternative products that are latex-free must be used.